

Results: We included 109 LGG and 145 HGG patients with a median survival time of 1,490 and 511 days, respectively.

We compared Cox proportional hazards regression models with and without the cognitive domain by means of loglikelihood ratios tests (LRT), discriminative performance measures (by AUC), and risk classification. Their added prognostic value on top of known prognostic factors was assessed in two patient groups ). Methods: In a retrospective cohort study of patients undergoing awake craniotomy between 20 we performed pre-operative neuropsychological assessments in five cognitive domains. Our aim was to investigate whether pre-operative cognitive functioning is of added value in survival prediction in these patients.

3Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, Netherlands.2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.1University Medical Center Utrecht/UMC Utrecht Brain Center, Department of Neurology & Neurosurgery, Utrecht University, Utrecht, Netherlands.Huenges Wajer 1,3, Carla Ruis 1,3, Filip Y. Emma van Kessel 1 *, Ewoud Schuit 2, Irene M.
